%0 Journal Article %A Freney, Jean %A Brun, Yvonne %A Bes, Michele %A Meugnier, Helene %A Grimont, Francine %A Grimont, Patrick A. D. %A Nervi, Chantal %A Fleurette, Jean %T Staphylococcus lugdunensis sp. nov. and Staphylococcus schleiferi sp. nov., Two Species from Human Clinical Specimens %D 1988 %J International Journal of Systematic and Evolutionary Microbiology, %V 38 %N 2 %P 168-172 %@ 1466-5034 %R https://doi.org/10.1099/00207713-38-2-168 %I Microbiology Society, %X Deoxyribonucleic acid relatedness studies (S1 nuclease method) showed that 23 unidentified Staphylococcus strains form two homogeneous genomic species related 1 to 9% to 24 type strains representing known Staphylococcus species. These new species were named Staphylococcus lugdunensis and Staphylococcus schleiferi. Strains of S. lugdunensis were susceptible to novobiocin, produced a fibrinogen affinity factor, and failed to produce coagulase, heat-stable nuclease, and staphylokinase. S. lugdunensis strains differed from S. hominis (the phenotypically closest species) by production of ornithine decarboxylase and the fibrinogen affinity factor. The guanine-plus-cytosine content of the deoxyribonucleic acid was 32 mol%. The type strain is N860297 (= ATCC 43809). Strains of S. schleiferi were susceptible to novobiocin, produced a heat-stable nuclease and a fibrinogen affinity factor, and failed to produce coagulase and staphylokinase. S. schleiferi strains differed from S. aureus by production of an antigenically different heat-stable nuclease and the lack of pigmentation, free coagulase, protein A, and β-ribitol teichoic acid. The guanine-plus-cytosine content of the deoxyribonucleic acid was 37 mol%. The type strain is N850274 (= ATCC 43808). %U https://www.microbiologyresearch.org/content/journal/ijsem/10.1099/00207713-38-2-168