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Volume 49, Issue 4

A study of small-colony, β-haemolytic, Lancefield group C streptococci within the anginosus group: description of Streptococcus constellatus subsp. pharyngis subsp. nov., associated with the human throat and pharyngitis Free

Abstract

β-Haemolytic, Lancefield group within the anginosus-species group were shown by genetic and phenotypic criteria to be heterogeneous and to constitute two distinct taxa related at subspecies level to and , respectively. The first group, referred to here as DNA group 1, comprised six strains with 86–100% intragroup overall genomic DNA relatedness; five of the strains were originally isolated from the human throat and one was from an abdominal mass. They shared 61–77% DNA relatedness (Δ values = 1.2-1.5 °C) with reference strains of and were clearly differentiated from (now named subsp. ) by the ability to produce β-N-acetylgalactosaminidase, β-acetylglucosaminidase, β--fucosidase, β--galactosidase and β--glucosidase. The name subsp. is proposed for these strains on the grounds that they are genetically and phenotypically distinct and exhibit a predeliction for the human throat, being isolated also from cases of pharyngitis. The DNA G+C content is 35–37 mol%. The type strain is MM9889a (= NCTC 13122). The second group (DNA group 2) was formed by five β-haemolytic, Lancefield group C strains originally isolated from various human infections. DNA group 2 strains (81–100% intragroup DNA relatedness) shared 60–72% DNA relatedness (Δ values = 2.1-4.1 C) with strains NCTC 10713 and MAS 283 but were not dearly differentiated phenotypically from , showed no dear pattern of clinical association, and therefore are not formally proposed as a new subspecies here.

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Keyword(s): constellatus , human throat , pharyngitis , Streptococcus constellatus subsp and Streptococcus constellatus subsp. pharyngis subsp. nov
© 1999 International Union of of Microbiological Societies
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1999-10-01
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A study of small-colony, β-haemolytic, Lancefield group C streptococci within the anginosus group: description of Streptococcus constellatus subsp. pharyngis subsp. nov., associated with the human throat and pharyngitis
Int J Syst Evol Microbiol 49, 1443 (1999); https://doi.org/10.1099/00207713-49-4-1443
/content/journal/ijsem/10.1099/00207713-49-4-1443
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