%0 Journal Article %A Tian, Xin-Peng %A Long, Li-Juan %A Li, Su-Mei %A Zhang, Jing %A Xu, Ying %A He, Jie %A Li, Jie %A Wang, Fa-Zuo %A Li, Wen-Jun %A Zhang, Chang-Sheng %A Zhang, Si %T Pseudonocardia antitumoralis sp. nov., a deoxynyboquinone-producing actinomycete isolated from a deep-sea sediment %D 2013 %J International Journal of Systematic and Evolutionary Microbiology, %V 63 %N Pt_3 %P 893-899 %@ 1466-5034 %R https://doi.org/10.1099/ijs.0.037135-0 %I Microbiology Society, %X An aerobic actinomycete, designated SCSIO 01299T, was isolated from a deep-sea sediment collected from the northern South China Sea at a depth of 3258 m. The isolate was found to be a natural producer of the synthesized antitumour agent deoxynyboquinone and its three new derivatives, pseudonocardians A, B and C. A blast search based on almost-complete 16S rRNA gene sequences showed that strain SCSIO 01299T had high sequence similarities with members of the genus Pseudonocardia . The 16S rRNA gene sequence phylogenetic tree revealed that strain SCSIO 01299T was a member of the genus Pseudonocardia . Phenotypic analysis, chemotaxonomy and DNA–DNA relatedness could readily distinguish the isolate from established members in this genus. It was concluded that strain SCSIO 01299T represents a novel species, for which the name Pseudonocardia antitumoralis sp. nov. is proposed. The type strain is SCSIO 01299T ( = DSM 45322T  = CCTCC M 2011255T). %U https://www.microbiologyresearch.org/content/journal/ijsem/10.1099/ijs.0.037135-0