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Volume 63, Issue Pt_7

Taxonomy of the Anginosus group of the genus and description of subsp. subsp. nov. and subsp. subsp. nov. Open Access

Abstract

The Anginosus group of the genus has been the subject of much taxonomic confusion, which has hampered the full appreciation of its clinical significance. The purpose of this study was to critically re-examine the taxonomy of the Anginosus group, with special attention to β-haemolytic, Lancefield group C strains, using multilocus sequence analysis (MLSA) combined with 16S rRNA gene sequence and phenotypic analyses. Phylogenetic analysis of concatenated sequences of seven housekeeping genes previously used for examination of viridans streptococci distinguished seven distinct and coherent clusters in the Anginosus group. Analyses of 16S rRNA gene sequences and phenotypic characters supported the MLSA clustering and currently recognized taxa of the Anginosus group. Single gene analyses showed considerable allele sharing between species, thereby invalidating identification based on single-locus sequencing. Two novel clusters of β-haemolytic, Lancefield group C strains within the and species and isolated from patients with sore throat showed sufficient phylogenetic distances from other clusters to warrant status as novel subspecies. The novel cluster within was identified as the previously recognized DNA homology cluster, DNA group 2. The names subsp. subsp. nov. (type strain CCUG 39159 = DSM 25818 = SK1267) and subsp. subsp. nov. (type strain SK1359 = CCUG 62387 = DSM 25819) are proposed.

  • Published Online:
Funding
This study was supported by the:
  • Faculty of Health Sciences, Aarhus University
  • Danish Medical Research Council (Award 271-08-0808)
© 2013 IUMS
  • This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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2013-07-01
2024-05-10
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Taxonomy of the Anginosus group of the genus Streptococcus and description of Streptococcus anginosus subsp. whileyi subsp. nov. and Streptococcus constellatus subsp. viborgensis subsp. nov.
Int J Syst Evol Microbiol 63, 2506 (2013); https://doi.org/10.1099/ijs.0.043232-0
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