@article{mbs:/content/journal/ijsem/10.1099/ijsem.0.001195, author = "Ahn, Sharon and Jin, Tae-Eun and Chang, Dong-Ho and Rhee, Moon-Soo and Kim, Hyun Ju and Lee, Sang Jun and Park, Doo-Sang and Kim, Byoung-Chan", title = "Agathobaculum butyriciproducens gen. nov.  sp. nov., a strict anaerobic, butyrate-producing gut bacterium isolated from human faeces and reclassification of Eubacterium desmolans as Agathobaculum desmolans comb. nov.", journal= "International Journal of Systematic and Evolutionary Microbiology", year = "2016", volume = "66", number = "9", pages = "3656-3661", doi = "https://doi.org/10.1099/ijsem.0.001195", url = "https://www.microbiologyresearch.org/content/journal/ijsem/10.1099/ijsem.0.001195", publisher = "Microbiology Society", issn = "1466-5034", type = "Journal Article", keywords = "butyrate", keywords = "Eubacterium", keywords = "human gut microbe", keywords = "Agathobaculum", keywords = "anaerobic", keywords = "gastrointestinal tract", abstract = "A novel bacterial strain, SR79T, was isolated from a Korean faecal sample and characterized using a polyphasic approach. SR79T was found to be a strictly anaerobic, Gram-stain-positive, non-spore-forming, non-motile, catalase- and oxidase-negative short rod with no flagella. SR79T grew optimally at 37 °C in the presence of 0.5 % (w/v) NaCl at pH 7. The NaCl range for growth was 0–1 % (w/v). The isolate produced butyric acid (>18  mM) as a major end product. A phylogenetic analysis based on 16S rRNA gene sequences revealed that the most closely related type strains were Eubacterium desmolans ATCC 43058T and Butyricicoccus pullicaecorum 25-3T (96.4 and 96.0 % similarity, respectively). The DNA G+C content was determined to be 52.9 mol%. The major cellular fatty acids (>10 %) were C16 : 0, C18 : 1 cis-9, C19 : 1 cyc 9,10 and C14 : 0. Meso-diaminopimelic acid was present in the cell wall peptidoglycan and the cell wall hydrolysates contained ribose, glucose and galactose. The 16S rRNA gene sequence similarity, phylogenetic analysis, chemotaxonomic and phenotypic characteristics allowed differentiation of SR79T, which represents a novel species of a new genus within the family Ruminococcaceae , for which the name Agathobaculum butyriciproducens gen. nov. sp. nov. is proposed. The type strain is SR79T (=KCTC 15532T=DSM 100391T). Based on the results of this study, it is also proposed to transfer Eubacterium desmolans to this new genus, as Agathobaculum desmolans comb. nov. The type strain of Agathobaculum desmolans is ATCC 43058T (=CCUG 27818T).", }