@article{mbs:/content/journal/ijsem/10.1099/00207713-42-2-270, author = "Dame, John B. and Mahan, Suman M. and Yowell, Charles A.", title = "Phylogenetic Relationship of Cowdria ruminantium, Agent of Heartwater, to Anaplasma marginale and Other Members of the Order Rickettsiales Determined on the Basis of 16S rRNA Sequence†", journal= "International Journal of Systematic and Evolutionary Microbiology", year = "1992", volume = "42", number = "2", pages = "270-274", doi = "https://doi.org/10.1099/00207713-42-2-270", url = "https://www.microbiologyresearch.org/content/journal/ijsem/10.1099/00207713-42-2-270", publisher = "Microbiology Society", issn = "1466-5034", type = "Journal Article", abstract = "The phylogenetic relationship between Cowdria ruminantium and representative members of the orders Rickettsiales and Chlamydiales has been examined on the basis of the sequence of the 16S rRNA. Phylogeny reconstruction by using both parsimony and distance methods supports the conclusion that C. ruminantium is closely related to the Rickettsiales and in particular to the family Anaplasmataceae. A signature of nine base substitutions delineated the linkage of Anaplasma marginale with C. ruminantium and differentiated these two species from the 45 other members of the alpha group of Proteobacteria examined, and five of these base substitutions were unique among all members of the class Proteobacteria examined to date.", }