%0 Journal Article %A Cox, Laura M %A Sohn, Jiho %A Tyrrell, Kerin L %A Citron, Diane M %A Lawson, Paul A %A Patel, Nisha B %A Iizumi, Tadasu %A Perez-Perez, Guillermo I %A Goldstein, Ellie J. C %A Blaser, Martin J %T Description of two novel members of the family Erysipelotrichaceae: Ileibacteriumvalens gen. nov., sp. nov. and Dubosiella newyorkensis, gen. nov., sp. nov., from the murine intestine, and emendation to the description of Faecalibacterium rodentium %D 2017 %J International Journal of Systematic and Evolutionary Microbiology, %V 67 %N 5 %P 1247-1254 %@ 1466-5034 %R https://doi.org/10.1099/ijsem.0.001793 %K anaerobe %K Ileibacterium valens %K Dubosiella newyorkensis %K Erysipelotrichaceae %I Microbiology Society, %X To better characterize murine intestinal microbiota, a large number (187) of Gram-positive-staining, rod- and coccoid-shaped, and facultatively or strictly anaerobic bacteria were isolated from small and large intestinal contents from mice. Based on 16S rRNA gene sequencing, a total 115 isolates formed three phylogenetically distinct clusters located within the family Erysipelotrichaceae . Group 1, as represented by strain NYU-BL-A3T, was most closely related to Allobaculum stercoricanis , with 16S rRNA gene sequence similarity values of 87.7 %. A second group, represented by NYU-BL-A4T, was most closely related to Faecalibaculum rodentium , with 86.6 % 16S rRNA gene sequence similarity. A third group had a nearly identical 16S rRNA gene sequence (99.9 %) compared with the recently described Faecalibaculum rodentium , also recovered from a laboratory mouse; however, this strain had a few differences in biochemical characteristics, which are detailed in an emended description. The predominant (>10 %) cellular fatty acids of strain NYU-BL-A3T were C16 : 0 and C18 : 0, and those of strain NYU-BL-A4T were C10 : 0, C16 : 0, C18 : 0 and C18 : 1ω9c. The two groups could also be distinguished by multiple biochemical reactions, with the group represented by NYU-BL-A4T being considerably more active. Based on phylogenetic, biochemical and chemotaxonomic criteria, two novel genera are proposed, Ileibacterium valens gen. nov., sp. nov. with NYU-BL-A3T (=ATCC TSD-63T=DSM 103668T) as the type strain and Dubosiella newyorkensis gen. nov., sp. nov. with NYU-BL-A4T (=ATCC TSD-64T=DSM 103457T) as the type strain. %U https://www.microbiologyresearch.org/content/journal/ijsem/10.1099/ijsem.0.001793