1887

Abstract

complex is a group of rapidly growing, multiresistant mycobacteria previously divided into three species. Proposal for the union of and into one subspecies, so-called subsp. , created much confusion about the routine identification and reporting of clinical isolates for clinicians. Results derived from multigene sequencing unambiguously supported the reinstatement of and as species, culminating in the presence of (41)-encoded macrolide resistance in . Present genome-based analysis unambiguously supports the reinstatement of and as species after the average nucleotide identity values of 96.7 % for versus , and 96.4 % for versus , and the 96.6 % identity between and was put into the perspective of a larger, 28-species analysis. Accordingly, DNA–DNA hybridization values predicted by the complete gene sequencing analysis were between 68.7 and 72.3 % in this complex. These genomic data as well as the phenotypic characteristics prompted us to propose to reinstate the previously known and into two distinct species among the complex.

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2017-08-01
2024-03-29
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