Mycobacterium decipiens sp. nov., a new species closely related to the Mycobacterium tuberculosis complex
Brown-Elliott, Barbara A. and Simmer, Patricia J. and Trovato, Alberto and Hyle, Emily P. and Droz, Sara and Buckwalter, Seanne P. and Borroni, Emanuele and Branda, John A. and Iana, Elkina and Mariottini, Alessandro and Nelson, Jameelah and Matteelli, Alberto and Toney, Nadege C. and Scarparo, Claudio and de Man, Tom J. B. and Vasireddy, Ravikiran and Gandhi, Rajesh T. and Wengenack, Nancy L. and Cirillo, Daniela M. and Wallace, Richard J. and Tortoli, Enrico,, 68, 3557-3562 (2018),
doi = https://doi.org/10.1099/ijsem.0.003031,
publicationName = Microbiology Society,
issn = 1466-5026,
abstract= Two mycobacterial strains with close similarity to the Mycobacterium tuberculosis complex (MTBC) were isolated from cutaneous lesions of patients in the USA and Italy. At the phenotypic level, similarities to the MTBC included slow growth rate, rough morphotype of the unpigmented colonies and nearly identical high-performance liquid chromatography profiles of mycolic acids. In contrast to the MTBC, the strains were niacin- and nitrate-negative, and catalase-positive both at 68 °C and in semi-quantitative tests. The clinical isolates were more closely related to M. tuberculosis than to any other known mycobacterium and scored positive with commercial DNA probes (Hologic AccuProbe M. tuberculosis ). Both average nucleotide identity and genome-to-genome distance suggested the strains are different from the MTBC. Therefore, given the distinguishing phenotypic and genomic-scale differences, we submit that the strains belong to a new species we have named Mycobacterium decipiens with type strain TBL 1200985T (=ATCC TSD-117T=DSM 105360T).,
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