ICTV Virus Taxonomy Profile: Hypoviridae Suzuki, Nobuhiro and Ghabrial, Said A. and Kim, Kook-Hyung and Pearson, Michael and Marzano, Shin-Yi L. and Yaegashi, Hajime and Xie, Jiatao and Guo, Lihua and Kondo, Hideki and Koloniuk, Igor and Hillman, Bradley I. and ICTV Report Consortium,, 99, 615-616 (2018), doi = https://doi.org/10.1099/jgv.0.001055, publicationName = Microbiology Society, issn = 0022-1317, abstract= The Hypoviridae, comprising one genus, Hypovirus, is a family of capsidless viruses with positive-sense, ssRNA genomes of 9.1–12.7 kb that possess either a single large ORF or two ORFs. The ORFs appear to be translated from genomic RNA by non-canonical mechanisms, i.e. internal ribosome entry site-mediated and stop/restart translation. Hypoviruses have been detected in ascomycetous or basidiomycetous filamentous fungi, and are considered to be replicated in host Golgi-derived, lipid vesicles that contain their dsRNA as a replicative form. Some hypoviruses induce hypovirulence to host fungi, while others do not. This is a summary of the current ICTV report on the taxonomy of the Hypoviridae, which is available at www.ictv.global/report/hypoviridae., language=, type=