Molecular epidemiological analysis of Japanese encephalitis virus in China
Wang, Huan Yu and Takasaki, Tomohiko and Fu, Shi Hong and Sun, Xiao Hong and Zhang, Hai Lin and Wang, Zhao Xiao and Hao, Zong Yu and Zhang, Jia Ke and Tang, Qing and Kotaki, Akira and Tajima, Shigeru and Liang, Xiao Feng and Yang, Wei Zhong and Kurane, Ichiro and Liang, Guo Dong,, 88, 885-894 (2007),
doi = https://doi.org/10.1099/vir.0.82185-0,
publicationName = Microbiology Society,
issn = 0022-1317,
abstract= Sixty-two new Japanese encephalitis virus (JEV) isolates were obtained from mosquitoes, biting midges, human cerebrospinal fluid and human blood samples in China during 2002–2005. The E and prM genes were sequenced and phylogenetic analyses were performed with 38 JEV other isolates from China and 36 JEV strains from other countries. Phylogenetic trees based on the E and prM gene sequences were similar. The results indicate that: (i) recent JEV isolates from China are divided into two genotypes, genotype 1 and genotype 3; (ii) recent JEV isolates from China are grouped into the same clusters within genotypes 1 and 3; and (iii) genotype 1 JEV strains have been isolated in China since 1979, whilst genotype 3 JEV strains were isolated before the 1970s. The results suggest that genotype 1 JEV was introduced to China around 1979 and that JEV strains belonging to genotypes 1 and 3 circulate in China.,
language=,
type=