%0 Journal Article %A Choi, Seon Young %A Lee, Je Hee %A Jeon, Yoon-Seong %A Lee, Hye Ri %A Kim, Eun Jin %A Ansaruzzaman, M. %A Bhuiyan, Nurul A. %A Endtz, Hubert P. %A Niyogi, S. K. %A Sarkar, B. L. %A Nair, G. Balakrish %A Nguyen, Binh Minh %A Hien, Nguyen Tran %A Czerkinsky, Cecil %A Clemens, John D. %A Chun, Jongsik %A Kim, Dong Wook %T Multilocus variable-number tandem repeat analysis of Vibrio cholerae O1 El Tor strains harbouring classical toxin B %D 2010 %J Journal of Medical Microbiology, %V 59 %N 7 %P 763-769 %@ 1473-5644 %R https://doi.org/10.1099/jmm.0.017939-0 %K MLVA, multilocus variable-number tandem repeat analysis %K CT, cholera toxin %I Microbiology Society, %X Atypical Vibrio cholerae O1 strains – hybrid strains (strains that cannot be classified either as El Tor or classical biotype) and altered strains (El Tor biotype strains that produce classical cholera toxin) – are currently prevalent in Asia and Africa. A total of 74 hybrid and altered strains that harboured classical cholera toxin were investigated by multilocus variable-number tandem repeat analysis (MLVA). The results showed that the hybrid/altered strains could be categorized into three groups and that they were distant from the El Tor strain responsible for the seventh cholera pandemic. Hybrid/altered strains with a tandem repeat of the classical CTX prophage on the small chromosome were divided into two MLVA groups (group I: Mozambique/Bangladesh group; group III: Vietnam group), and altered strains with the RS1–CTX prophage containing the El Tor type rstR and classical ctxB on the large chromosome were placed in two MLVA groups (group II: India/Bangladesh group; group III: India/Vietnam group). %U https://www.microbiologyresearch.org/content/journal/jmm/10.1099/jmm.0.017939-0