RT Journal Article SR Electronic(1) A1 Park, Joo-Hee A1 Shim, Tae-Sun A1 Lee, Seung-Ae A1 Lee, Hyungki A1 Lee, In-Kyung A1 Kim, Kijeong A1 Kook, Yoon-Hoh A1 Kim, Bum-JoonYR 2010 T1 Molecular characterization of Mycobacterium intracellulare-related strains based on the sequence analysis of hsp65, internal transcribed spacer and 16S rRNA genes JF Journal of Medical Microbiology, VO 59 IS 9 SP 1037 OP 1043 DO https://doi.org/10.1099/jmm.0.020727-0 PB Microbiology Society, SN 1473-5644, AB We investigated the molecular epidemiological features of 94 Mycobacterium intracellulare-related strains, isolated from Korean patients, using sequence analysis targeting 3 independent chronometer molecules, hsp65, the internal transcribed spacer 1 region and the 16S rRNA gene. By collective consideration of these three gene-based approaches, the 94 strains were divided into 5 groups (INT1, INT2, INT3, INT4 and INT5). The frequencies of genotype INT1, 2, 3, 4 and 5 in the 94 isolates were 57.4 % (54), 27.7 % (26), 6.4 % (6), 5.3 % (5) and 3.2 % (3), respectively. When correlations between genotypes and clinical parameters (age, sex, radiological type and the presence of a cavity) were analysed in 78 patients with non-tuberculous mycobacteria pulmonary diseases, no relationships were observed with respect to age, sex and radiological type, but genotype and the presence of a cavity tended to be related (P=0.051)., UL https://www.microbiologyresearch.org/content/journal/jmm/10.1099/jmm.0.020727-0