RT Journal Article SR Electronic(1) A1 Hoskisson, Paul A.YR 2018 T1 Microbe Profile: Corynebacterium diphtheriae – an old foe always ready to seize opportunity JF Microbiology, VO 164 IS 6 SP 865 OP 867 DO https://doi.org/10.1099/mic.0.000627 PB Microbiology Society, SN 1465-2080, AB Corynebacterium diphtheriae is a globally important Gram-positive aerobic Actinobacterium capable of causing the toxin-mediated disease, diphtheria. Diphtheria was a major cause of childhood mortality prior to the introduction of the toxoid vaccine, yet it is capable of rapid resurgence following the breakdown of healthcare provision, vaccination or displacement of people. The mechanism and treatment of toxin-mediated disease is well understood, however there are key gaps in our knowledge on the basic biology of C. diphtheriae particularly relating to host colonisation, the nature of asymptomatic carriage, population genomics and host adaptation., UL https://www.microbiologyresearch.org/content/journal/micro/10.1099/mic.0.000627